2016年 · 第96卷第18期

One of the hallmarks of innovative ability and academic influence in the field of clinical medicine is the quantity and quality of published papers. China is already a big country in clinical research, but it is not a strong country. The number of published papers is in the forefront of the world, but the quality is not high. Improving the quality of papers as soon as possible is the consensus of all researchers in the field of clinical research, and it is also an important measure to implement the national strategy of innovation-driven development. Therefore, the author put forward suggestions to improve the writing quality of clinical research papers, and the report at the National Medical Journal Editor Training Conference was recognized by the participating editors, and the report at the editorial board of some Chinese Medical Association series journals was recognized by the participating clinical experts. This article will explain the principle behind the suggestions and the problems to be paid attention to in practice. I hope these suggestions will help to improve the writing quality of clinical research papers in China.

With the rapid development of robotic surgery all over the world, minimally invasive surgery has gradually transitioned from the era of ordinary laparoscopy to the era of robotic surgery. Due to unfamiliarity with the operating mode, most of the secondary injuries and surgical complications occur at the beginning of the surgeon's learning curve. The life safety of patients and the occupational safety of surgeons highlight the importance of surgical robot training efforts^[1]。 However, as of now, there is no recognized training standard for robot operation^[2,3]。 Including China, at present, most training bases worldwide use the recommended standards of Intuitive Surgical, a manufacturer of Da Vinci systems, which divides training into preclinical training (training center) and clinical training. Due to the high cost of preclinical training, the training effect is not satisfactory, and 2-d simulation training can only guarantee 50% of urologists to complete robot-assisted radical prostatectomy^[4]。 The ideal training system should ensure that the training results are quantifiable and controllable, each training stage is efficiently connected and closely related to clinical work, and multiple robot training centers cooperate together. At the same time, the training of junior doctors should be included in routine. This paper will synthesize the robotic training center of Lorraine University in France and the existing experience of robot training in China^[5,6]Based on the successful development of robot-assisted training system, a new training system for surgical robots is discussed.

Primary liver cancer (hereinafter referred to as liver cancer) ranks 6th in the incidence of malignant tumors in the world, and more than 50% of new cases and deaths of liver cancer every year occur in China^[1]。 The latest data from registered tumor areas in China show that the incidence of liver cancer ranks 4th among malignant tumors and the mortality ranks 3rd among malignant tumors^[2]。 With the development of modern medical science and technology, the treatment of liver cancer has made great progress. However, because the clinical symptoms of early liver cancer are not obvious, 70% ~80% of patients are in the advanced stage when they see a doctor. At present, the overall prognosis of liver cancer treatment is still not ideal.

Cerebrovascular reactivity (CVR) refers to the response of cerebral blood vessels to stimulation (such as cerebral perfusion pressure, arterial blood CO₂The ability to contract and relax when partial pressure level changes) can reflect the reserve capacity of cerebral blood vessels^[1]。 In which cerebral blood vessels follow arterial blood CO₂Partial pressure (PaCO₂The nature of changes in levels is called cerebrovascular carbon dioxide reactivity (CVR-CO₂)。 By detecting CVR-CO₂It can evaluate the regulatory ability of cerebrovascular and collateral circulation state, and has important significance for early diagnosis, treatment and prognostic evaluation of many diseases (stroke, cognitive dysfunction, etc.). In this paper, the influencing factors, detection methods and clinical application of cerebrovascular carbon dioxide reactivity are reviewed.