2015年 · 第95卷第20期

Acute gastrointestinal hemorrhage is one of the common medical emergencies in clinic. Implementing rapid and effective diagnosis and treatment for patients at the first time is the key to saving patients' lives and improving their prognosis. Therefore, in clinical work, it is a clinical skill that every physician should master to quickly judge the cause of gastrointestinal bleeding, accurately assess the severity of the disease, and take appropriate measures for different situations.

stress ulcer (SU) refers to acute gastrointestinal mucosal erosion, ulcer and other lesions that occur in various stressful states such as severe trauma, critical illness or severe mental illness. In severe cases, it can be complicated by gastrointestinal bleeding or even perforation, which can aggravate and worsen the original disease and increase the mortality rate. Therefore, prevention of SU is a link that cannot be ignored in the treatment of critically ill patients. SU can be manifested as acute gastric mucosal lesions, acute erosive gastritis, acute hemorrhagic gastritis, peptic ulcer, etc. under endoscopy.

A 51-year-old female was admitted to the hospital mainly for "anorexia, fatigue for 6 months and fever in the afternoon for 20 days". The patient developed anorexia, general fatigue and weight loss of approximately 4 kg without obvious trigger 6 months ago. Afternoon fever occurred 20 days ago, with a maximum body temperature of 39 ℃. There was no fear of cold, night sweats, no cough, expectoration and hemoptysis, no nausea, vomiting, no abdominal pain, abdominal distension and diarrhea, and the body temperature could drop to normal after symptomatic treatment. Abdominal B-ultrasound was performed in other hospitals to find multiple liver mass occupation, and multiple liver metastases were considered. An ultrasound-guided liver biopsy was performed in an external hospital, and the result was chronic granulomatous inflammation of the liver, showing caseous necrosis, and no acid-fast bacilli were found in acid-fast staining. Considering inflammatory lesions, neoplastic lesions were not excluded. 30 years of prior chronic viral hepatitis B (hepatitis B) history. Physical examination showed no obvious positive signs.

inflammatory bowel disease (IBD) is a chronic recurrent disease of the gastrointestinal tract, mainly including ulcerative colitis (UC) and Crohn's disease (CD). Epidemiological surveys show that the incidence of IBD in developing countries has increased significantly in the past 20 years. IBD can greatly affect the quality of life of patients and is related to the occurrence of intestinal malignant tumors. It has become one of the hotspots of modern gastrointestinal diseases. The etiology of IBD is unclear, and it is currently believed to be related to many factors such as genetics, immunity, infection and environment. In recent years, many studies have suggested that gastrointestinal microorganisms are related to the pathogenesis of IBD, but the specific pathogens are still unclear. Helicobacter pylori (H.pylori, HP) is a common gram-negative microaerobic bacterium belonging to the genus Helicobacter that has been in symbiosis with humans for more than 50 000 years. Many studies have confirmed that HP infection is closely related to a variety of digestive tract diseases^[1]。 In recent years, many studies have found that HP infection and inflammatory bowel disease are also related, but the conclusions of each study are not consistent. This paper reviews the research and progress of the relationship between HP infection and IBD, in order to have a more comprehensive understanding of the relationship between the two diseases, and to develop a new understanding of the nature and treatment of IBD.

On the occasion of the 100th anniversary of the founding of Chinese Medical Journal, the 100th Anniversary of the Founding of Chinese Medical Journal and the Summit Forum on High-tech Medical Development and Internet Medical Care, sponsored by the Editorial Committee of Chinese Medical Journal and Huashan Hospital affiliated to Fudan University and co-organized by Registration Network, was grandly held in Shanghai, the birthplace of Chinese Medical Journal, on March 28th, 2015. More than 350 experts and scholars from all over the country attended the event. Professor Chen Xiangmei of PLA General Hospital, Academician of Chinese Academy of Engineering, Professor Wang Chen, President of Sino-Japanese Hospital, Academician of Chinese Academy of Engineering, Professor Ge Junbo of Zhongshan Hospital affiliated to Fudan University, Academician of Chinese Academy of Sciences, and Professor Hejie, President of Cancer Hospital of Chinese Academy of Medical Sciences, Academician of Chinese Academy of Sciences, respectively wrote inscriptions and called to express warm congratulations on the convening of the meeting. Chen Xinshi, deputy editor-in-chief and director of the editorial department of Chinese Medical Journal, edited and reviewed, and Professor Zhang Qunhua of Huashan Hospital affiliated to Fudan University co-hosted the conference.